"I'm Not the God of Medicine" tells the story of Cheng Yong, the owner of a sacred oil shop, from a male health care product vendor who could not pay the rent to become the exclusive agent of the generic drug "Glenin" in India, but also because of his own irregularities. Drug transportation and trafficking violated the law and was sentenced to jail.

Wait, we are a formal logistics company, all of which deliver life-saving medicine, but we are engaged in legal transportation.

Learn the law, know the law, abide by the law

So today the editor is going to take you to understand the real cold chain transportation of medicines. Cold chain medicines: refers to medicines that require refrigeration and freezing temperatures for the storage and transportation of medicines. For example, hospitals use large amounts of blood products, various insulins, antibiotics, etc., most cold chain drugs need to be stored and transported under strictly limited indicators and ensure that the validity period and efficacy of the drugs are not lost. Among them, the important thing is to keep the low temperature and constant temperature state uninterruptedly, so that the logistics process of cold chain drugs during the delivery, transfer, and handover period and the use unit meet the specified refrigeration requirements without "broken chain." This time the editor will introduce the domestic cold chain transportation of drugs from three dimensions: the impact conditions of drug transportation, the cold chain drug management system, and the common cold chain drugs.

Influencing conditions of drug transportation

 Temperature has a great influence on the quality of medicines, too high or too low can make the medicines deteriorate and fail and cause losses. In particular, biological products, blood products, insulins, vaccines, and most targeted preparations and monoclonal antibodies can only be stored within a suitable prescribed temperature range in order to minimize the impact of temperature on the quality of medicines. If the temperature is too low, there will be a process of freezing and thawing of the medicine due to the freezing of the medicine (freezing and thawing refers to the physical effect and phenomenon of freezing and thawing due to the temperature falling below zero and rising above zero), leading to the occurrence of some drug properties Changes, which in turn may denature or invalidate the drug.

Domestic drug cold chain management system

1. The transportation of refrigerated medicines must use refrigerated containers, and corresponding refrigerated equipment must be equipped when receiving refrigerated medicines.

2. During the transportation of refrigerated medicines, the personnel who distribute, transport and receive refrigerated medicines shall conduct temperature monitoring and recording.

3. Cold chain equipment must be used exclusively for special purposes and must not be used for other purposes.

4. The refrigerated medicines must be stored in the cold chain system and kept by a dedicated person.

Fifth, temperature monitoring should be carried out during the storage of refrigerated medicines.

Measure the temperature of refrigerated medicines every day after get off work and before work, and record the monitoring results faithfully; keep records of power outages, shutdowns, and fault maintenance, and make shifts when the administrator cannot perform routine monitoring when going out for some reason.

6. Stored refrigerated medicines should be placed neatly. There should be a gap of 1-2cm between the refrigerated medicines and the wall, and the refrigerated medicines should be placed according to the product name and expiration date.

Seven, cold chain equipment should be maintained frequently, and the refrigerator should be kept clean to ensure that it is free of dust and stains. The evaporator of the refrigerator should be defrosted and defrosted in time if the frosting temperature exceeds 4 hours. If it is not used for a long time, it should be Wipe the inside and outside of the box and turn it on for 2 hours a week. Refrigerators and refrigerated backpacks have been used to wipe off water marks to keep the boxes dry and clean.

8. Abnormalities or failures of cold chain equipment should be reported in time, inspected and repaired by professionals, and non-professional technicians are not allowed to disassemble it casually.

Common medicines that require refrigeration

Alprostadil fat emulsion injection, recombinant human tumor necrosis factor receptor antibody fusion protein for injection, heparin sodium injection, recombinant human erythropoietin for injection (CHO cells), oxytocin injection, freeze-dried human fibrin Proto, posterior pituitary injection, tetanus antitoxin, flurbiprofen axetil injection, octreotide acetate injection, recombinant human granulocyte stimulating factor injection, batroxobin injection, intravenous human immunoglobulin (PH4), Salmon calcitonin nasal spray, salmon calcitonin injection, thymosin for injection, α1 insulin injection, protamine biosynthesis human insulin injection (30R premix), insulin aspart 30 injection, protamine zinc recombinant lysine Insulin pro (25R) mixed injection, recombinant human insulin injection, protamine zinc recombinant human insulin mixed injection, insulin glargine injection, prefilled snake venom hemagglutinin injection, oral live bifidobacterium preparation, recombinant human Interferon, recombinant human growth hormone, stimulating factor, thymosin, human placental tissue fluid, growth hormone and analogs, erythropoietin and analogs, etc. Human albumin, globulin, human immunoglobulin, human coagulation factor, thrombin freeze-dried powder, freeze-dried human fibrinogen, etc. Various vaccines for tetanus antitoxin, hepatitis A and B vaccine. Jinshuangqi tablets, salmon calcitonin injection, vinorelbine tartrate injection, cytochrome C solution, setpa injection, semustine capsules, leucovorin injection, etoposide soft capsules, benzenesulfonate for injection Cisatracurium, Octreotide Acetate for Injection, Vindesine Sulfate for Injection, Vinblastine Sulfate for Injection, Vincristine Sulfate for Injection, Urokinase for Injection, Cefathiazin for Injection, Cefoperazone Sodium for Injection, Injection Use thymus method, cytarabine hydrochloride for injection, ifosfamide for injection, etc.

I have introduced so much to everyone, and everyone can be said to have a general understanding of my country's drug supply chain management. We are the real drug god, speeding up the running of drugs and escorting life!